Read the equation
This current uses the same conductance-times-driving-force structure as the AMPA expression, multiplied by B(V). The additional factor reduces current under magnesium block and changes with membrane voltage. The code separately tracks a rising variable and a slowly decaying synaptic state.
Terms & definitions
| Term | Meaning in this source |
|---|---|
| g_NMDA | Maximum conductance |
| s | Synaptic state |
| B | Voltage-dependent block factor |
| E_NMDA | Reversal potential |
How it works
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Assumptions & limits
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Original context
Read the surrounding source passage
void step(float dt) {
s *= std::exp(-dt / tau);
}
};
// NMDA Receptor (slow excitatory, voltage-dependent Mg2+ block)
// I_NMDA = g_NMDA * s * B(V) * (V - E_NMDA)
// B(V) = 1 / (1 + [Mg2+]_o * exp(-0.062*V) / 3.57)
struct NMDASynapse {
float g_max = 0.5f; // nS
float E_rev = 0.0f; // mV
float tau_rise = 2.0f; // ms
float tau_decay = 100.0f;// ms - NMDA is slow!
float Mg_o = 1.0f; // mM - External Mg2+ concentration
float s = 0.0f;
float x = 0.0f; // Rise variable
Exact original notation
I_NMDA = g_NMDA * s * B(V) * (V - E_NMDA)